What is the prognosis (outlook) for people with Castleman disease?

What is the prognosis (outlook) for people with Castleman disease?

The outlook is very good for most people with unicentric Castleman disease (UCD) who have the affected lymph node removed. Surgery is typically considered curative. When treated, this condition does not usually affect life expectancy.

The prognosis for people with multicentric Castleman disease (MCD) varies. Some people need ongoing treatments because the disease never goes away fully. In these cases, doctors determine a treatment plan that may include chemotherapy and other therapies to keep the condition from getting worse for as long as possible.