What causes Chiari malformation?

What causes Chiari malformation?

Chiari malformation has multiple causes. Chiari malformation is caused by a structural defect in the brain and spinal cord that happens while a baby is developing in the womb. Some investigators also believe that the structural defect in the skull (smaller than normal size in the area where the cerebellum sits) leads to the crowding and pressure on the brain that pushes it through the foramen magnum where the brain and spinal cord meets.

Because Chiari malformations have occurred in more than one family member, the disorder might also be inherited (passed down through families) in some cases.

Some researchers believe a lack of certain nutrients during pregnancy may play a role.

Chiari malformations are almost always present at birth, though symptoms may not develop until later in life. Very rarely, a Chiari malformation can develop in someone who was not born with the disorder. In these cases, the skull or spinal cord might change shape due to tumors, irregularities of the spine or hematomas.