What are the symptoms of central pontine myelinolysis?

What are the symptoms of central pontine myelinolysis?

Symptoms of CPM usually appear several days after the rapid correction of sodium levels. These can vary depending on where in your brain the myelination is and how much damage there is, but may include:

  • Behavioral changes.
  • Confusion.
  • Difficulty speaking (dysarthria).
  • Difficulty swallowing (dysphagia).
  • Facial paralysis.
  • Muscle weakness.
  • Loss of balance and coordination.
  • Involuntary muscle movement and tremors.
  • Irregular eye movements (oculomotor dysfunction).
  • Parkinsonism (Parkinson’s disease-like symptoms, such as tremors and speech difficulties).
  • Quadriparesis (weakness in both arms and legs).

In severe cases, CPM causes paralysis of all muscles except for your eye muscles (locked-in syndrome), coma or death.

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