What are the symptoms of Castleman disease?

What are the symptoms of Castleman disease?

Signs and symptoms of Castleman disease vary depending on the type. People with unicentric Castleman disease (UCD) do not always have symptoms. Doctors usually discover the disease during an exam for another condition. When symptoms do occur, they include:

  • Pressure or full feeling in the abdomen (belly) or chest
  • Lump beneath the skin in the armpit, neck, or groin
  • Unexplained weight loss

Signs of multicentric Castleman disease (MCD) include:

  • Fever
  • Night sweats
  • Fatigue (extreme tiredness)
  • Appetite and weight loss
  • Abnormally large lymph nodes, typically in the neck, armpit, collarbone, and groin
  • Enlarged spleen or liver
  • Anemia (low amount of red blood cells)

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