Can non-Hodgkins’s lymphoma (NHL) come back?

Can non-Hodgkins’s lymphoma (NHL) come back?

Yes. Most relapses of aggressive NHL occur within two years of treatment. Relapses of indolent lymphoma can occur later.

NHL might recur in two types of situations. In one, the NHL was never completely cured during treatment and so requires additional kinds of treatment. In the second, the disease was put into remission and then returns. This is called relapsed disease. It might happen because the slow-growing cells of low-grade lymphoma might not be affected by the treatment (which tends to kill faster-growing cells).