What causes chilblain lupus?

What causes chilblain lupus?

Chilblain lupus can be inherited or sporadic. Sporadic chilblain lupus means you develop the condition later in life, usually as an adult. Doctors don’t know why it occurs.

People with inherited chilblain lupus have a gene mutation (change). A change in either of these genes can lead to chilblain lupus:

• SAMHD1 genes play a role in your immune response.
• TREX1 helps with DNA repair.