How is autoimmune hemolytic anemia treated?

How is autoimmune hemolytic anemia treated?

Autoimmune hemolytic anemia treatment usually involves addressing underlying conditions first. For example, if your AIHA is linked to lupus, then your healthcare provider will probably start by treating the lupus directly. If AIHA is caused by lymphoma, treating the lymphoma directly is important. If AIHA is associated with a certain drug, you’ll likely stop taking that medication. In addition, people with mild AIHA may not need treatment at all.


Corticosteroids help weaken your body’s immune response. That’s why they’re typically the first line of treatment for autoimmune hemolytic anemia. If corticosteroids don’t work, then your healthcare provider may prescribe immunosuppressants. The goal is to stop your immune system from attacking your bone marrow.


When medications don’t work, you may need surgery to remove your spleen. Your spleen is responsible for eliminating abnormal red blood cells from your bloodstream, including those with antibodies. The spleen also houses antibody-producing cells. A splenectomy can help preserve red blood cells, reducing the risk of anemia.

Blood transfusion

In severe cases, people with AIHA may need a blood transfusion.

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