Who does cytokine release syndrome affect?

Who does cytokine release syndrome affect?

Cytokine storm may affect those who are receiving immunotherapy for cancer. These treatments include checkpoint inhibitors and CAR T-cell therapy.

CRS can also develop as a result of infection. When your body comes into contact with a virus or other type of infection, it triggers your immune system. Sometimes, your immune system overreacts, releasing more cytokines than it should. This results in CRS.

Cytokine release syndrome may also occur in people infected with COVID-19. This is part of the reason why some people develop life-threatening complications.

People with autoimmune diseases and certain genetic syndromes may be more prone to developing CRS.