What’s the difference between Cushing’s syndrome (Hypercortisolism) and Cushing’s disease?

What’s the difference between Cushing’s syndrome (Hypercortisolism) and Cushing’s disease?

Cushing’s disease is a type of Cushing’s syndrome. Cushing’s disease is caused by a benign tumor located in the pituitary gland that secretes too much ACTH (adrenocorticotropic hormone), which in turn increases cortisol.

Out of patients with Cushing’s syndrome, Cushing’s disease accounts for more than 70% of cases in adults and about 60% to 70% of cases in children and adolescents.