What is the prognosis (outlook) of Angelman syndrome?

What is the prognosis (outlook) of Angelman syndrome?

The prognosis (outlook) for someone with Angelman syndrome depends on several factors, including:

• The genetic cause (big deletions of the UBE3A gene have a worse prognosis).
• Your child's age at diagnosis.
• The severity of symptoms.
• The level of intervention and therapy your child is able to receive to manage their symptoms.

Most people with Angelman syndrome will have a normal life span. They won’t have any developmental regression, and their behavioral symptoms might improve with self-help skills and supportive care.

Most people with Angelman syndrome need constant care and attention due to their behavior. Prognosis improves significantly with early diagnosis and interventions like speech, physical and occupational therapies.