What is cytokine release syndrome?

What is cytokine release syndrome?

Cytokine release syndrome (CRS) — sometimes called cytokine storm or cytokine-associated toxicity — is a condition that develops when your immune system responds too aggressively to infection. It can also happen after certain types of immunotherapy, such as CAR T-Cell Therapy.

With CRS, your body releases chemicals called cytokines. This process can result in a number of different symptoms and manifestations. People with CRS typically develop fever and a variety of other symptoms, which can affect multiple organs. Prompt treatment is key to reducing these exaggerated immune responses.