What causes epidermal inclusion cysts?

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What causes epidermal inclusion cysts?

Most epidermal inclusion cysts occur at random.

Some genetic conditions may be associated with the development of multiple epidermal inclusion cysts:

  • Gardner Syndrome (Familial Colorectal Polyposis).
  • Gorlin Syndrome (Basal Cell Nevus Syndrome).
  • Favre-Racouchot syndrome.

Medications that may be associated with an increased the risk of developing epidermal inclusion cysts include:

  • BRAF inhibitors.
  • Imiquimod.
  • Cyclosporine.

Epidermal inclusion cysts are formed from the follicular infundibulum, which is part of the hair follicle. Epidermal inclusion cysts form when the follicular infundibulum is disrupted, or when the surface of the skin becomes implanted below the skin through an injury or trauma in the area, such as a scratch, surgical wound or a skin condition like acne.

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