What causes dextrocardia?
What causes dextrocardia?
Dextrocardia appears to be caused by genetic changes early in pregnancy. More than 60 genes play a role in how your organs are positioned in your body. Researchers are still looking for the specific gene that causes dextrocardia.
About 1 in 4 people with dextrocardia also have primary ciliary dyskinesia. Mutations in more than 30 different genes, including DNAI1 and DNAH5, can cause this genetic disorder. Some people can be a “carrier,” meaning they have a genetic mutation but no symptoms of the condition. If both your parents are carriers, you have a 25% chance of having primary ciliary dyskinesia (with symptoms) and a 50% chance of being a carrier.