What causes cyclic neutropenia (CyN)?

What causes cyclic neutropenia (CyN)?

CyN can occur later in life or be congenital (present from birth), but generally presents becomes evident right after birth. CyN is caused by a change in the genetic instructions (a mutation) to make an enzyme for fighting infection. Neutropenia symptoms result when the bone marrow does not produce enough neutrophils, when neutrophils die early, or when these cells do not perform correctly.