What causes amenorrhea?

What causes amenorrhea?

The different types of amenorrhea have different causes.

Common causes of primary amenorrhea include:

  • Chromosomal or genetic problem with the ovaries (the female sex organs that hold the eggs).
  • Hormonal issues stemming from problems with the hypothalamus or the pituitary gland.
  • Structural problem with the reproductive organs, such as missing parts of the reproductive system.

Common causes of secondary amenorrhea include:

  • Pregnancy (which is the most common cause of secondary amenorrhea).
  • Breastfeeding.
  • Menopause.
  • Some birth control methods, such as Depo Provera, intrauterine devices (IUDs) and certain birth control pills.
  • Chemotherapy and radiation therapy for cancer.
  • Previous uterine surgery with subsequent scarring (for example, if you had a dilation and curettage, often called D&C).

Other causes of secondary amenorrhea can include:

  • Stress.
  • Poor nutrition.
  • Weight changes — extreme weight loss or obesity.
  • Exercising associated with low weight.
  • Ongoing illness or chronic illness.

You may also have conditions that can cause secondary amenorrhea:

  • Primary ovarian insufficiency, when you experience menopause before age 40.
  • Hypothalamus disorders, such as functional hypothalamic amenorrhea (FHA) — which is also called hypothalamic amenorrhea (HA). FHA is a condition where amenorrhea is associated with stress or weight loss, but isn’t clearly caused by an organic issue with a woman’s body.
  • Pituitary disorders, such as a benign pituitary tumor or excessive production of prolactin.
  • Other hormonal problems, such as polycystic ovary syndrome, adrenal disorders or hypothyroidism.
  • Ovarian tumors.
  • Surgery to remove uterus or ovaries.

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