What causes ALD?

What causes ALD?

The cause of ALD is a mutation in a particular gene. Your genes are the instruction manual for creating proteins that have critical roles in how the body works. With a genetic mutation, the gene may create faulty protein.

With ALD, there’s a problem with the ABCD1 gene, which creates the ALDP protein. This protein helps break down VLCFAs. Because of the faulty protein, VLCFAs accumulate in the body’s tissues.