What are the signs and symptoms of ATTR amyloidosis?

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What are the signs and symptoms of ATTR amyloidosis?

ATTR amyloidosis can affect many organs. Symptoms depend on the organs that are involved.

Symptoms indicating the arms are affected include:

  • Carpal tunnel syndrome.
  • Numbness, burning and/or tingling (peripheral neuropathy).
  • Biceps tendon rupture.

Symptoms indicating the back is affected include:

  • Lumbar spinal stenosis.

Symptoms indicating the legs are affected include:

  • Swelling of the feet or legs.
  • Numbness, burning and/or tingling (peripheral neuropathy).
  • Leg weakness.

Symptoms indicating the head and neck are affected include:

  • Eye floaters (vitreous opacities).
  • Lightheadedness upon standing.

Symptoms indicating the heart and lungs are affected include:

  • Shortness of breath.
  • Palpitations.
  • Chest pain.
  • Fatigue.

Symptoms indicating the stomach or intestines are affected include:

  • Poor appetite.
  • Bloating or excessive gas.
  • Diarrhea or constipation.

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