How many types of epidermolysis bullosa are there?

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How many types of epidermolysis bullosa are there?

EB has four primary subtypes:

  • EB simplex (EBS). EBS is the most common form of EB, and it can range from mild (not very painful) to severe (very painful). Blisters develop in the top layer of your skin (epidermis). The blisters rarely scar after they’ve healed.
  • Junctional EB (JEB). JEB causes blisters to form in your mouth and airway. It’s rare, and it can range from moderate (uncomfortable, mild pain) to severe.
  • Dystrophic EB (DEB). DEB causes blisters to grow in the middle layer of your skin (dermis). It can range from mild to severe.
  • Kindler syndrome. In Kindler syndrome, blisters can form in all layers of your skin. It’s very rare.

Healthcare providers diagnose EBS, JEB and DEB according to your affected layers of skin. Kindler syndrome may appear as blisters throughout different layers of your skin.

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