Are cerebral cavernous hemangiomas hereditary?
About 20% of cavernous malformations are genetic (run in families). These are caused by a mutation in any one of three genes. If you have a cavernous malformation, your children have about a 50% chance of having one too. Having more than one cerebral cavernous hemangioma is more common in people with a family history. People with a genetic link are also more likely to develop new cavernous hemangiomas over time.
People at higher risk for the hereditary form are:
- Descendants of the original Hispanic population of New Mexico.
- European-American descendants from Oklahoma and the deep South.
- People of Ashkenazi Jewish descent.