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These conditions can be caused by family genetics and are often known as heritable disorders of connective tissue. Connective tissue diseases can also be caused by things that exist in the environment. Non-inherited causes of autoimmune types of connective tissue disease may include:

  • Exposure to toxic chemicals, such as those found in air pollution and cigarette smoke.
  • Exposure to ultraviolet light.
  • Inadequate nutrition, including lack of vitamins D and C.
  • Infections.


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