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Critical limb ischemia is severely blocked blood flow to your one or multiple of your hands, legs or feet. It causes intense pain, numbness and slow-healing sores on your feet, legs or hands. It is a serious condition that increases your risk of heart complications, limb amputation and death.

Critical limb ischemia is a severe stage of peripheral artery disease (PAD). PAD occurs when a fatty substance called plaque (atherosclerotic plaque) builds up inside your arteries and restricts blood flow. It’s harder for your muscles and tissue to remain healthy and strong, or to heal, with limited blood flow. Another name for critical limb ischemia is chronic limb-threatening ischemia.

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Critical limb ischemia is a severe stage of peripheral artery disease, in which you have significant blockages in the blood flow to your arms, legs or feet. This increases your risk of heart complications. Some people need an amputation to treat critical limb ischemia. The sooner you get treatment, the higher your chances of a good outcome.
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Chronic limb-threatening ischemia occurs when you have severely blocked blood flow to your hands, legs or feet. It is an advanced stage of peripheral artery disease. Critical limb ischemia significantly increases your risk of heart problems and a shorter lifespan. Getting treatment right away improves your chances of a good outcome, including avoiding amputation.
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