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The causes of CJD are as follows:

  • Sporadic (unknown cause): 85% and 90% of cases.
  • Genetic CJD (conditions inherited from one or both parents): 10% to 15% of cases.
  • Acquired CJD (infection from a medical procedure, such as a transplant or tissue graft): Less than 1% of cases.
  • Variant CJD (contracted by eating beef from an animal with bovine spongiform encephalopathy): Only 232 confirmed cases since 1986. The most recent person with variant CJD died in 2019.
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